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FOXN1 deficient nude severe combined immunodeficiency

Nude severe combined immunodeficiency is a rare inherited disease caused by autosomal recessive loss-of-function mutations in FOXN1. This gene encodes a transcription factor essential for the development of the thymus, the primary lymphoid organ that supports T-cell development and selection. To dat...

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Bibliographic Details
Published in:Orphanet J Rare Dis
Main Authors: Rota, Ioanna A., Dhalla, Fatima
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225657/
https://ncbi.nlm.nih.gov/pubmed/28077132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-016-0557-1
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