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Multi-cellular natural killer (NK) cell clusters enhance NK cell activation through localizing IL-2 within the cluster
Multi-cellular cluster formation of natural killer (NK) cells occurs during in vivo priming and potentiates their activation to IL-2. However, the precise mechanism underlying this synergy within NK cell clusters remains unclear. We employed lymphocyte-laden microwell technologies to modulate contac...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225448/ https://ncbi.nlm.nih.gov/pubmed/28074895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40623 |
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