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The APC/C Coordinates Retinal Differentiation with G1 Arrest through the Nek2-Dependent Modulation of Wingless Signaling

The cell cycle is coordinated with differentiation during animal development. Here we report a cell-cycle-independent developmental role for a master cell-cycle regulator, the anaphase-promoting complex or cyclosome (APC/C), in the regulation of cell fate through modulation of Wingless (Wg) signalin...

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Pubblicato in:Dev Cell
Autori principali: Martins, Torcato, Meghini, Francesco, Florio, Francesca, Kimata, Yuu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225405/
https://ncbi.nlm.nih.gov/pubmed/28041905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.12.005
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