Chronic Phenotype Characterization of a Large-Animal Model of Hereditary Tyrosinemia Type 1

Hereditary tyrosinemia type 1 (HT1) is an autosomal recessive disease caused by deficiency in fumarylacetoacetate hydrolase, the last enzyme in the tyrosine catabolic pathway. In this study, we investigated whether fumarylacetoacetate hydrolase deficient (FAH(−/−)) pigs, a novel large-animal model o...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Elgilani, Faysal, Mao, Shennen A., Glorioso, Jaime M., Yin, Meng, Iankov, Ianko D., Singh, Anisha, Amiot, Bruce, Rinaldo, Piero, Marler, Ronald J., Ehman, Richard L., Grompe, Markus, Lillegard, Joseph B., Hickey, Raymond D., Nyberg, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2017
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225308/
https://ncbi.nlm.nih.gov/pubmed/27855279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.09.013
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados