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Differences in Microsatellite Instability Profiles between Endometrioid and Colorectal Cancers: A Potential Cause for False-Negative Results?

Colorectal (CRCs) and endometrioid (EMCs) cancers in patients with Lynch syndrome exhibit microsatellite instability (MSI) detected by PCR or immunohistochemistry (IHC). While both assays are equally sensitive for CRCs, some suggest that PCR has a higher false-negative rate than IHC in EMCs. We asse...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Diagn
Egile Nagusiak: Wang, Yang, Shi, Chanjuan, Eisenberg, Rosana, Vnencak-Jones, Cindy L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Investigative Pathology 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225298/
https://ncbi.nlm.nih.gov/pubmed/27810331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmoldx.2016.07.008
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