2,3,7,8 Tetrachlorodibenzo-p-dioxin-induced RNA abundance changes identify Ackr3, Col18a1, Cyb5a and Glud1 as candidate mediators of toxicity

2,3,7,8 Tetrachlorodibenzo-p-dioxin (TCDD) is an aromatic, long-lived environmental contaminant. While the pathogenesis of TCDD-induced toxicity is poorly understood, it has been shown that the aryl hydrocarbon receptor (AHR) is required. However, the specific transcriptomic changes that lead to tox...

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Dettagli Bibliografici
Pubblicato in:Arch Toxicol
Autori principali: Watson, John D., Prokopec, Stephenie D., Smith, Ashley B., Okey, Allan B., Pohjanvirta, Raimo, Boutros, Paul C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2016
Soggetti:
Molecular Toxicology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225275/
https://ncbi.nlm.nih.gov/pubmed/27136898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-016-1720-0
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