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γδ T cells coexpressing gut homing α4β7 and αE integrins define a novel subset promoting intestinal inflammation

γδ T lymphocytes, dominant T cell subsets in the intestine, mediate both regulatory and pathogenic roles, yet the mechanisms underlying such opposing effects remain unclear. Here, we identified a unique γδ T cell subset that co-expresses high levels of gut homing integrins, CD103 and α4β7. They were...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Do, Jeong-su, Kim, Sohee, Keslar, Karen, Jang, Eunjung, Huang, Emina, Fairchild, Robert L., Pizarro, Theresa T., Min, Booki
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225242/
https://ncbi.nlm.nih.gov/pubmed/27927968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601060
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