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γδ T cells coexpressing gut homing α4β7 and αE integrins define a novel subset promoting intestinal inflammation
γδ T lymphocytes, dominant T cell subsets in the intestine, mediate both regulatory and pathogenic roles, yet the mechanisms underlying such opposing effects remain unclear. Here, we identified a unique γδ T cell subset that co-expresses high levels of gut homing integrins, CD103 and α4β7. They were...
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Publicado no: | J Immunol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5225242/ https://ncbi.nlm.nih.gov/pubmed/27927968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601060 |
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