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IL-1β is a key cytokine that induces trypsin upregulation in the influenza virus–cytokine–trypsin cycle

Severe influenza is characterized by a cytokine storm, and the influenza virus–cytokine–trypsin cycle is one of the important mechanisms of viral multiplication and multiple organ failure. The aim of this study was to define the key cytokine(s) responsible for trypsin upregulation. Mice were infecte...

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Détails bibliographiques
Publié dans:Arch Virol
Auteurs principaux: Indalao, I. L., Sawabuchi, T., Takahashi, E., Kido, H.
Format: Artigo
Langue:Inglês
Publié: Springer Vienna 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225228/
https://ncbi.nlm.nih.gov/pubmed/27714503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00705-016-3093-3
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