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Putative model for heat shock protein 70 complexation with receptor of advanced glycation end products through fluorescence proximity assays and normal mode analyses

Extracellular heat shock protein 70 (HSP70) is recognized by receptors on the plasma membrane, such as Toll-like receptor 4 (TLR4), TLR2, CD14, and CD40. This leads to activation of nuclear factor-kappa B (NF-κB), release of pro-inflammatory cytokines, enhancement of the phagocytic activity of innat...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Grunwald, Marcelo Sartori, Ligabue-Braun, Rodrigo, Souza, Cristiane Santos, Heimfarth, Luana, Verli, Hugo, Gelain, Daniel Pens, Moreira, José Cláudio Fonseca
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225064/
https://ncbi.nlm.nih.gov/pubmed/27858225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0746-9
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