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Sublethal endoplasmic reticulum stress caused by the mutation of immunoglobulin heavy chain-binding protein induces the synthesis of a mitochondrial protein, pyrroline-5-carboxylate reductase 1

Most human neurodegenerative diseases are sporadic and appear later in life. Aging and neurodegeneration are closely associated, and recent investigations reveal that endoplasmic reticulum (ER) stress is involved in the progression of these features. Immunoglobulin heavy chain-binding protein (BiP)...

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Bibliografske podrobnosti
izdano v:Cell Stress Chaperones
Main Authors: Jin, Hisayo, Komita, Mari, Koseki, Haruhiko, Aoe, Tomohiko
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225059/
https://ncbi.nlm.nih.gov/pubmed/27796797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-016-0741-1
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