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APC/C(Fzr/Cdh1) dependent regulation of Planar Cell Polarity establishment via Nek2 kinase acting on Dishevelled

The Anaphase Promoting Complex/Cyclosome (APC/C) is an E3 ubiquitin ligase, well known for its role in cell cycle progression. However, it has been linked to additional functions, mainly in neuronal contexts, when using the co-activator Cdh1/Fzr. Here, our data indicate a post-mitotic requirement fo...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Weber, Ursula, Mlodzik, Marek
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225046/
https://ncbi.nlm.nih.gov/pubmed/28041906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.12.006
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