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Comprehensive N-Glycan Profiling of Cetuximab Biosimilar Candidate by NP-HPLC and MALDI-MS

Monitoring glycosylation of the mAbs have been emphasized and routinely characterized in biopharmaceutical industries because the carbohydrate components are closely related to the safety, efficacy, and consistency of the antibodies. In this study, the comprehensive glycan profiling of a biosimilar...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Sheng, Gao, Wenjie, Wang, Yao, He, Zhenyu, Feng, Xiaojun, Liu, Bi-Feng, Liu, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225015/
https://ncbi.nlm.nih.gov/pubmed/28072827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0170013
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