Increased PD-1 Expression and Altered T Cell Repertoire Diversity Predict Mortality in Patients with Septic Shock: A Preliminary Study

Sepsis causes impairment of innate and adaptive immunity by multiple mechanisms, including depletion of immune effector cells and T cell exhaustion. Although lymphocyte dysfunction is associated with increased mortality and potential reactivation of latent viral infection in patients with septic sho...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Tomino, Atsutoshi, Tsuda, Masanobu, Aoki, Ruri, Kajita, Yuka, Hashiba, Masamitsu, Terajima, Tsuguaki, Kano, Hideki, Takeyama, Naoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5225000/
https://ncbi.nlm.nih.gov/pubmed/28072859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169653
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