D19S Mutation of the Cationic, Cysteine-Rich Protein PAF: Novel Insights into Its Structural Dynamics, Thermal Unfolding and Antifungal Function

The cysteine-rich, cationic, antifungal protein PAF is abundantly secreted into the culture supernatant of the filamentous Ascomycete Penicillium chrysogenum. The five β-strands of PAF form a compact β-barrel that is stabilized by three disulphide bonds. The folding of PAF allows the formation of fo...

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Publicado en:PLoS One
Autores principales: Sonderegger, Christoph, Fizil, Ádám, Burtscher, Laura, Hajdu, Dorottya, Muñoz, Alberto, Gáspári, Zoltán, Read, Nick D., Batta, Gyula, Marx, Florentine
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224997/
https://ncbi.nlm.nih.gov/pubmed/28072824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169920
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