Dietary Chromium Restriction of Pregnant Mice Changes the Methylation Status of Hepatic Genes Involved with Insulin Signaling in Adult Male Offspring

Maternal undernutrition is linked with an elevated risk of diabetes mellitus in offspring regardless of the postnatal dietary status. This is also found in maternal micro-nutrition deficiency, especial chromium which is a key glucose regulator. We investigated whether maternal chromium restriction c...

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Publicat a:PLoS One
Autors principals: Zhang, Qian, Sun, Xiaofang, Xiao, Xinhua, Zheng, Jia, Li, Ming, Yu, Miao, Ping, Fan, Wang, Zhixin, Qi, Cuijuan, Wang, Tong, Wang, Xiaojing
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224989/
https://ncbi.nlm.nih.gov/pubmed/28072825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169889
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