Mice lacking sialyltransferase ST3Gal-II develop late-onset obesity and insulin resistance

Sialyltransferases are a family of 20 gene products in mice and humans that transfer sialic acid from its activated precursor, CMP-sialic acid, to the terminus of glycoprotein and glycolipid acceptors. ST3Gal-II (coded by the St3gal2 gene) transfers sialic acid preferentially to the three positions...

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Detalhes bibliográficos
Publicado no:Glycobiology
Main Authors: Lopez, Pablo HH, Aja, Susan, Aoki, Kazuhiro, Seldin, Marcus M, Lei, Xia, Ronnett, Gabriele V, Wong, G William, Schnaar, Ronald L
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Original articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224593/
https://ncbi.nlm.nih.gov/pubmed/27683310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cww098
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