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Methods to increase reproducibility in differential gene expression via meta-analysis

Findings from clinical and biological studies are often not reproducible when tested in independent cohorts. Due to the testing of a large number of hypotheses and relatively small sample sizes, results from whole-genome expression studies in particular are often not reproducible. Compared to single...

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Publicat a:Nucleic Acids Res
Autors principals: Sweeney, Timothy E., Haynes, Winston A., Vallania, Francesco, Ioannidis, John P., Khatri, Purvesh
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224496/
https://ncbi.nlm.nih.gov/pubmed/27634930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw797
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