Visualization of self-delivering hydrophobically modified siRNA cellular internalization

siRNAs are a new class of therapeutic modalities with promising clinical efficacy that requires modification or formulation for delivery to the tissue and cell of interest. Conjugation of siRNAs to lipophilic groups supports efficient cellular uptake by a mechanism that is not well characterized. He...

詳細記述

保存先:
書誌詳細
出版年:Nucleic Acids Res
主要な著者: Ly, Socheata, Navaroli, Deanna M., Didiot, Marie-Cécile, Cardia, James, Pandarinathan, Lakshmipathi, Alterman, Julia F., Fogarty, Kevin, Standley, Clive, Lifshitz, Lawrence M., Bellve, Karl D., Prot, Matthieu, Echeverria, Dimas, Corvera, Silvia, Khvorova, Anastasia
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2017
主題:
Chemical Biology and Nucleic Acid Chemistry
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5224471/
https://ncbi.nlm.nih.gov/pubmed/27899655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1005
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