Motility of glioblastoma cells is driven by netrin-1 induced gain of stemness

BACKGROUND: Glioblastoma is an untreatable brain cancer. The tumors contain a population of stem-like cells which are highly invasive and resistant to therapies. These cells are the main reason for the lethality of glioblastoma. Extracellular guidance molecule netrin-1 promotes the invasiveness and...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Ylivinkka, Irene, Sihto, Harri, Tynninen, Olli, Hu, Yizhou, Laakso, Aki, Kivisaari, Riku, Laakkonen, Pirjo, Keski-Oja, Jorma, Hyytiäinen, Marko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223529/
https://ncbi.nlm.nih.gov/pubmed/28069038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0482-0
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