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Drift Barriers to Quality Control When Genes Are Expressed at Different Levels

Gene expression is imperfect, sometimes leading to toxic products. Solutions take two forms: globally reducing error rates, or ensuring that the consequences of erroneous expression are relatively harmless. The latter is optimal, but because it must evolve independently at so many loci, it is subjec...

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Bibliografiske detaljer
Udgivet i:Genetics
Main Authors: Xiong, Kun, McEntee, Jay P., Porfirio, David J., Masel, Joanna
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223517/
https://ncbi.nlm.nih.gov/pubmed/27838629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.116.192567
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