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Looking beyond the brain to improve the pathogenic understanding of Parkinson’s disease: implications of whole transcriptome profiling of Patients’ skin

BACKGROUND: Parkinson’s Disease is a progressive neurodegenerative disease, characterized by symptoms of motor impairment, resulting from the loss of dopaminergic neurons in the midbrain, however non-neuronal symptoms are also common. Although great advances have been made in the pathogenic understa...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:BMC Neurol
Hauptverfasser: Planken, Anu, Kurvits, Lille, Reimann, Ene, Kadastik-Eerme, Liis, Kingo, Külli, Kõks, Sulev, Taba, Pille
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223462/
https://ncbi.nlm.nih.gov/pubmed/28068941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-016-0784-z
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