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Dabrafenib and trametinib activity in a patient with BRAF V600E mutated and microsatellite instability high (MSI-H) metastatic endometrial cancer

BACKGROUND: Targeting BRAF V600E mutation has been proven effective in the treatment of several types of cancer. In endometrial adenocarcinoma, the BRAF V600E mutation has been rarely reported. Whether targeting BRAF oncogene may represent a plausible therapeutic strategy for the rare patients with...

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Dades bibliogràfiques
Publicat a:Exp Hematol Oncol
Autors principals: Moschetta, Michele, Mak, Gabriel, Hauser, Joana, Davies, Catriona, Uccello, Mario, Arkenau, Hendrik-Tobias
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223353/
https://ncbi.nlm.nih.gov/pubmed/28078189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40164-016-0061-2
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