Myeloperoxidase-oxidized high density lipoprotein impairs atherosclerotic plaque stability by inhibiting smooth muscle cell migration

BACKGROUND: High density lipoprotein (HDL) has been proved to be a protective factor for coronary heart disease. Notably, HDL in atherosclerotic plaques can be nitrated (NO(2)-oxHDL) and chlorinated (Cl-oxHDL) by myeloperoxidase (MPO), likely compromising its cardiovascular protective effects. METHO...

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Bibliographic Details
Published in:Lipids Health Dis
Main Authors: Zhou, Boda, Zu, Lingyun, Chen, Yong, Zheng, Xilong, Wang, Yuhui, Pan, Bing, Dong, Min, Zhou, Enchen, Zhao, Mingming, Zhang, Youyi, Zheng, Lemin, Gao, Wei
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223295/
https://ncbi.nlm.nih.gov/pubmed/28069011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-016-0388-z
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