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Innate immune signaling and regulation in cancer immunotherapy

A pre-existing T cell-inflamed tumor microenvironment has prognostic utility and also can be predictive for response to contemporary cancer immunotherapies. The generation of a spontaneous T cell response against tumor-associated antigens depends on innate immune activation, which drives type I inte...

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Pubblicato in:Cell Res
Autori principali: Corrales, Leticia, Matson, Vyara, Flood, Blake, Spranger, Stefani, Gajewski, Thomas F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223230/
https://ncbi.nlm.nih.gov/pubmed/27981969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.149
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