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Polychlorinated biphenyls target Notch/Dll and VEGF R2 in the mouse placenta and human trophoblast cell lines for their anti-angiogenic effects

The intrauterine environment is particularly vulnerable to environmental exposures. We previously established a mouse model that provided evidence for pregnancy complications and placental anti-angiogenesis in response to Aroclor 1254 (A-1254), a mixture of polychlorinated biphenyls (PCBs). Importan...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Kalkunte, Satyan, Huang, Zheping, Lippe, Eliana, Kumar, Sunil, Robertson, Larry W., Sharma, Surendra
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223111/
https://ncbi.nlm.nih.gov/pubmed/28071720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39885
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