Genome-wide Trans-ethnic Meta-analysis Identifies Seven Genetic Loci Influencing Erythrocyte Traits and a Role for RBPMS in Erythropoiesis

Genome-wide association studies (GWASs) have identified loci for erythrocyte traits in primarily European ancestry populations. We conducted GWAS meta-analyses of six erythrocyte traits in 71,638 individuals from European, East Asian, and African ancestries using a Bayesian approach to account for h...

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Detalhes bibliográficos
Publicado no:Am J Hum Genet
Main Authors: van Rooij, Frank J.A., Qayyum, Rehan, Smith, Albert V., Zhou, Yi, Trompet, Stella, Tanaka, Toshiko, Keller, Margaux F., Chang, Li-Ching, Schmidt, Helena, Yang, Min-Lee, Chen, Ming-Huei, Hayes, James, Johnson, Andrew D., Yanek, Lisa R., Mueller, Christian, Lange, Leslie, Floyd, James S., Ghanbari, Mohsen, Zonderman, Alan B., Jukema, J. Wouter, Hofman, Albert, van Duijn, Cornelia M., Desch, Karl C., Saba, Yasaman, Ozel, Ayse B., Snively, Beverly M., Wu, Jer-Yuarn, Schmidt, Reinhold, Fornage, Myriam, Klein, Robert J., Fox, Caroline S., Matsuda, Koichi, Kamatani, Naoyuki, Wild, Philipp S., Stott, David J., Ford, Ian, Slagboom, P. Eline, Yang, Jaden, Chu, Audrey Y., Lambert, Amy J., Uitterlinden, André G., Franco, Oscar H., Hofer, Edith, Ginsburg, David, Hu, Bella, Keating, Brendan, Schick, Ursula M., Brody, Jennifer A., Li, Jun Z., Chen, Zhao, Zeller, Tanja, Guralnik, Jack M., Chasman, Daniel I., Peters, Luanne L., Kubo, Michiaki, Becker, Diane M., Li, Jin, Eiriksdottir, Gudny, Rotter, Jerome I., Levy, Daniel, Grossmann, Vera, Patel, Kushang V., Chen, Chien-Hsiun, Ridker, Paul M., Tang, Hua, Launer, Lenore J., Rice, Kenneth M., Li-Gao, Ruifang, Ferrucci, Luigi, Evans, Michelle K., Choudhuri, Avik, Trompouki, Eirini, Abraham, Brian J., Yang, Song, Takahashi, Atsushi, Kamatani, Yoichiro, Kooperberg, Charles, Harris, Tamara B., Jee, Sun Ha, Coresh, Josef, Tsai, Fuu-Jen, Longo, Dan L., Chen, Yuan-Tsong, Felix, Janine F., Yang, Qiong, Psaty, Bruce M., Boerwinkle, Eric, Becker, Lewis C., Mook-Kanamori, Dennis O., Wilson, James G., Gudnason, Vilmundur, O'Donnell, Christopher J., Dehghan, Abbas, Cupples, L. Adrienne, Nalls, Michael A., Morris, Andrew P., Okada, Yukinori, Reiner, Alexander P., Zon, Leonard I., Ganesh, Santhi K.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5223059/
https://ncbi.nlm.nih.gov/pubmed/28017375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2016.11.016
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