Novel Real-Time PCR Assay for Detection of Helicobacter pylori Infection and Simultaneous Clarithromycin Susceptibility Testing of Stool and Biopsy Specimens

A biprobe real-time PCR protocol, followed by hybridization melting point analysis, to detect point mutations in the 23S rRNA gene of Helicobacter pylori associated with clarithromycin resistance was established and evaluated in a clinical study. Of 92 patients who underwent endoscopy, 45 were found...

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Autori principali: Schabereiter-Gurtner, Claudia, Hirschl, Alexander M., Dragosics, Brigitte, Hufnagl, Peter, Puz, Sonja, Kovách, Zsuzsanna, Rotter, Manfred, Makristathis, Athanasios
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2004
Soggetti:
Bacteriology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC522301/
https://ncbi.nlm.nih.gov/pubmed/15472302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.10.4512-4518.2004
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