Death Receptor 3 Promotes Chemokine-Directed Leukocyte Recruitment in Acute Resolving Inflammation and Is Essential for Pathological Development of Mesothelial Fibrosis in Chronic Disease

Death receptor 3 (DR3; TNFRSF25) and its tumor necrosis factor–like ligand TL1A (TNFSF15) control several processes in inflammatory diseases through the expansion of effector T cells and the induction of proinflammatory cytokines from myeloid and innate lymphoid cells. Using wild-type (DR3(+/+)) and...

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Pubblicato in:Am J Pathol
Autori principali: Perks, William V., Singh, Ravinder K., Jones, Gareth W., Twohig, Jason P., Williams, Anwen S., Humphreys, Ian R., Taylor, Philip R., Jones, Simon A., Wang, Eddie C.Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2016
Soggetti:
Short Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222966/
https://ncbi.nlm.nih.gov/pubmed/27664471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.07.021
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