Polydeoxyribonucleotide, an Adenosine-A2(A) Receptor Agonist, Preserves Blood Testis Barrier from Cadmium-Induced Injury

Cadmium (Cd) impairs blood-testis barrier (BTB). Polydeoxyribonucleotide (PDRN), an adenosine A(2A) agonist, has positive effects on male reproductive system. We investigated the effects of PDRN on the morphological and functional changes induced by Cd in mice testes. Adult Swiss mice were divided i...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Squadrito, Francesco, Micali, Antonio, Rinaldi, Mariagrazia, Irrera, Natasha, Marini, Herbert, Puzzolo, Domenico, Pisani, Antonina, Lorenzini, Cesare, Valenti, Andrea, Laurà, Rosaria, Germanà, Antonino, Bitto, Alessandra, Pizzino, Gabriele, Pallio, Giovanni, Altavilla, Domenica, Minutoli, Letteria
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222826/
https://ncbi.nlm.nih.gov/pubmed/28119612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00537
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