Nuclear Pre-mRNA Decapping and 5′ Degradation in Yeast Require the Lsm2-8p Complex

Previous analyses have identified related cytoplasmic Lsm1-7p and nuclear Lsm2-8p complexes. Here we report that mature heat shock and MET mRNAs that are trapped in the nucleus due to a block in mRNA export were strongly stabilized in strains lacking Lsm6p or the nucleus-specific Lsm8p protein but n...

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Bibliographic Details
Main Authors:	Kufel, Joanna, Bousquet-Antonelli, Cecile, Beggs, Jean D., Tollervey, David
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology 2004
Subjects:	Gene Expression
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC522261/ https://ncbi.nlm.nih.gov/pubmed/15485930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.21.9646-9657.2004
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Nuclear Pre-mRNA Decapping and 5′ Degradation in Yeast Require the Lsm2-8p Complex

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