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Spatiotemporal coupling and decoupling of gene transcription with DNA replication origins during embryogenesis in C. elegans

The primary task of developing embryos is genome replication, yet how DNA replication is integrated with the profound cellular changes that occur through development is largely unknown. Using an approach to map DNA replication at high resolution in C. elegans, we show that replication origins are ma...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pourkarimi, Ehsan, Bellush, James M, Whitehouse, Iestyn
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5222557/
https://ncbi.nlm.nih.gov/pubmed/28009254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.21728
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