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Genomic Studies with Escherichia coli MelR Protein: Applications of Chromatin Immunoprecipitation and Microarrays

Escherichia coli MelR protein is a transcription activator that is essential for melibiose-dependent expression of the melAB genes. We have used chromatin immunoprecipitation to study the binding of MelR and RNA polymerase to the melAB promoter in vivo. Our results show that MelR is associated with...

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Detalhes bibliográficos
Main Authors: Grainger, David C., Overton, Timothy W., Reppas, Nikos, Wade, Joseph T., Tamai, Eiji, Hobman, Jon L., Constantinidou, Chrystala, Struhl, Kevin, Church, George, Busby, Stephen J. W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522211/
https://ncbi.nlm.nih.gov/pubmed/15466047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.20.6938-6943.2004
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