CIL-102-Induced Cell Cycle Arrest and Apoptosis in Colorectal Cancer Cells via Upregulation of p21 and GADD45

CIL-102 (1-[4-(furo[2,3-b]quinolin-4-ylamino)phenyl]ethanone) is a well-known, major active agent of the alkaloid derivative of Camptotheca acuminata with valuable biological properties, including anti-tumorigenic activity. In this study, we investigated the molecular mechanisms by which CIL-102 med...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huang, Wen-Shih, Kuo, Yi-Hung, Kuo, Hsing-Chun, Hsieh, Meng-Chiao, Huang, Cheng-Yi, Lee, Ko-Chao, Lee, Kam-Fai, Shen, Chien-Heng, Tung, Shui-Yi, Teng, Chih-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221879/
https://ncbi.nlm.nih.gov/pubmed/28068431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168989
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