Inhibition of Pterygium Fibroblast Migration and Outgrowth by Bevacizumab and Cyclosporine A Involves Down-Regulation of Matrix Metalloproteinases-3 and -13

We examined the connection between matrix metalloproteinase (MMP) expression/activity and pterygium fibroblast migration, and how these were affected by bevacizumab and/or cyclosporine A (CsA). Fibroblasts were obtained from 20 pterygia and 6 normal conjunctival specimens. Expression levels of MMP-3...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Yeoun-Hee, Jung, Jae-Chang, Gum, Sang Il, Park, Su-Bin, Ma, Jin Yeul, Kim, Yong Il, Lee, Kyoo Won, Park, Young Jeung
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221804/
https://ncbi.nlm.nih.gov/pubmed/28068383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169675
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