Hypoxia Regulates mTORC1-Mediated Keratinocyte Motility and Migration via the AMPK Pathway

Keratinocyte migration, the initial event and rate-limiting step in wound healing, plays a vital role in restoration of the intact skin barrier, also known as re-epithelialization. After acute tissue injury, hypoxic microenvironment gradually develops and acts as an early stimulus to initiate the he...

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Bibliographic Details
Published in:PLoS One
Main Authors: Yan, Tiantian, Zhang, Junhui, Tang, Di, Zhang, Xingyue, Jiang, Xupin, Zhao, Liping, Zhang, Qiong, Zhang, Dongxia, Huang, Yuesheng
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221764/
https://ncbi.nlm.nih.gov/pubmed/28068384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0169155
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