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Spikelets in Pyramidal Neurons: Action Potentials Initiated in the Axon Initial Segment That Do Not Activate the Soma

Spikelets are small spike-like depolarizations that can be measured in somatic intracellular recordings. Their origin in pyramidal neurons remains controversial. To explain spikelet generation, we propose a novel single-cell mechanism: somato-dendritic input generates action potentials at the axon i...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Michalikova, Martina, Remme, Michiel W. H., Kempter, Richard
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221759/
https://ncbi.nlm.nih.gov/pubmed/28068338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005237
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