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Model-guided optogenetic study of PKA signaling in budding yeast

In eukaryotes, protein kinase A (PKA) is a master regulator of cell proliferation and survival. The activity of PKA is subject to elaborate control and exhibits complex time dynamics. To probe the quantitative attributes of PKA dynamics in the yeast Saccharomyces cerevisiae, we developed an optogene...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Stewart-Ornstein, Jacob, Chen, Susan, Bhatnagar, Rajat, Weissman, Jonathan S., El-Samad, Hana
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221627/
https://ncbi.nlm.nih.gov/pubmed/28035051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0354
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