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Opposing roles for distinct LINC complexes in regulation of the small GTPase RhoA

Linker of Nucleoskeleton and Cytoskeleton (LINC) complexes span the nuclear envelope and transduce force from dynamic cytoskeletal networks to the nuclear lamina. Here we show that LINC complexes also signal from the nuclear envelope to critical regulators of the actin cytoskeleton. Specifically, we...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Main Authors: Thakar, Ketan, May, Christopher K., Rogers, Anna, Carroll, Christopher W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221622/
https://ncbi.nlm.nih.gov/pubmed/28035049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-06-0467
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