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Golgi enzymes do not cycle through the endoplasmic reticulum during protein secretion or mitosis

Golgi-specific sialyltransferase (ST) expressed as a chimera with the rapamycin-binding domain of mTOR, FRB, relocates to the endoplasmic reticulum (ER) in cells exposed to rapamycin that also express invariant chain (Ii)-FKBP in the ER. This result has been taken to indicate that Golgi-resident enz...

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Publicat a:Mol Biol Cell
Autors principals: Villeneuve, Julien, Duran, Juan, Scarpa, Margherita, Bassaganyas, Laia, Van Galen, Josse, Malhotra, Vivek
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5221618/
https://ncbi.nlm.nih.gov/pubmed/27807044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-08-0560
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