Capilliposide from Lysimachia capillipes inhibits AKT activation and restores gefitinib sensitivity in human non-small cell lung cancer cells with acquired gefitinib resistance

Most gefitinib-treated patients with non-small cell lung cancer (NSCLC) would eventually develop resistance. Lysimachia capillipes (LC) capilliposide extracts from LC Hemsl. show both in vitro and in vivo anti-cancer effects. In this study we investigated whether LC capilliposide in combination with...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Acta Pharmacol Sin
Egile Nagusiak: Zhang, Shi-rong, Xu, Ya-si, Jin, Er, Zhu, Lu-cheng, Xia, Bing, Chen, Xu-feng, Li, Fan-zhu, Ma, Sheng-lin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2017
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220541/
https://ncbi.nlm.nih.gov/pubmed/27840409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.116
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