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The natural product 4,10-aromadendranediol induces neuritogenesis in neuronal cells in vitro through activation of the ERK pathway

Recent studies focus on promoting neurite outgrowth to remodel the central nervous network after brain injury. Currently, however, there are few drugs treating brain diseases in the clinic by enhancing neurite outgrowth. In this study, we established an NGF-induced PC12 differentiation model to scre...

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Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Chang, Sai, Ruan, Wen-chen, Xu, Ya-zhou, Wang, Yun-jie, Pang, Jie, Zhang, Lu-yong, Liao, Hong, Pang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220540/
https://ncbi.nlm.nih.gov/pubmed/27840407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.115
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