Small interfering RNA targeting Fas protects mice against renal ischemia-reperfusion injury

Fas-mediated apoptosis has been suggested to contribute to tubular cell death after renal ischemia-reperfusion injury. Here we investigate whether small interfering RNA (siRNA) duplexes targeting Fas protect mice from acute renal failure after clamping of the renal artery. Renal ischemia-reperfusion...

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Detalhes bibliográficos
Main Authors: Hamar, Péter, Song, Erwei, Kökény, Gabor, Chen, Allen, Ouyang, Nengtai, Lieberman, Judy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC522049/
https://ncbi.nlm.nih.gov/pubmed/15466709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406421101
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