Fermentable carbohydrate stimulates FFAR2-dependent colonic PYY cell expansion to increase satiety

OBJECTIVE: Dietary supplementation with fermentable carbohydrate protects against body weight gain. Fermentation by the resident gut microbiota produces short-chain fatty acids, which act at free fatty acid receptor 2 (FFAR2). Our aim was to test the hypothesis that FFAR2 is important in regulating...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Brooks, Lucy, Viardot, Alexander, Tsakmaki, Anastasia, Stolarczyk, Emilie, Howard, Jane K., Cani, Patrice D., Everard, Amandine, Sleeth, Michelle L., Psichas, Arianna, Anastasovskaj, Jelena, Bell, Jimmy D., Bell-Anderson, Kim, Mackay, Charles R., Ghatei, Mohammad A., Bloom, Stephen R., Frost, Gary, Bewick, Gavin A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220466/
https://ncbi.nlm.nih.gov/pubmed/28123937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.10.011
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