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Phosphatidylinositol (4,5) bisphosphate regulates HIV-1 Gag targeting to the plasma membrane

A critical early event in the HIV type 1 (HIV-1) particle assembly pathway is the targeting of the Gag protein to the site of virus assembly. In many cell types, assembly takes place predominantly at the plasma membrane. Cellular factors that regulate Gag targeting remain undefined. The phosphoinosi...

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Bibliografiske detaljer
Main Authors: Ono, Akira, Ablan, Sherimay D., Lockett, Stephen J., Nagashima, Kunio, Freed, Eric O.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2004
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC522033/
https://ncbi.nlm.nih.gov/pubmed/15465916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405596101
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