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The mechanism of catalysis by type-II NADH:quinone oxidoreductases

Type II NADH:quinone oxidoreductase (NDH-2) is central to the respiratory chains of many organisms. It is not present in mammals so may be exploited as an antimicrobial drug target or used as a substitute for dysfunctional respiratory complex I in neuromuscular disorders. NDH-2 is a single-subunit m...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Blaza, James N., Bridges, Hannah R., Aragão, David, Dunn, Elyse A., Heikal, Adam, Cook, Gregory M., Nakatani, Yoshio, Hirst, Judy
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220320/
https://ncbi.nlm.nih.gov/pubmed/28067272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep40165
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