The neuropeptide TLQP-21 opposes obesity via C3aR1-mediated enhancement of adrenergic-induced lipolysis

OBJECTIVES: Obesity is characterized by excessive fat mass and is associated with serious diseases such as type 2 diabetes. Targeting excess fat mass by sustained lipolysis has been a major challenge for anti-obesity therapies due to unwanted side effects. TLQP-21, a neuropeptide encoded by the pro-...

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Bibliografiske detaljer
Udgivet i:Mol Metab
Main Authors: Cero, Cheryl, Razzoli, Maria, Han, Ruijun, Sahu, Bhavani Shankar, Patricelli, Jessica, Guo, ZengKui, Zaidman, Nathan A., Miles, John M., O'Grady, Scott M., Bartolomucci, Alessandro
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2016
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220279/
https://ncbi.nlm.nih.gov/pubmed/28123945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.10.005
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