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Sparsely populated folding intermediates of the Fyn SH3 domain: Matching native-centric essential dynamics and experiment
A complete description of how a protein folds requires the characterization of intermediate conformations traversed during the folding transition. We have calculated dynamics trajectories of a simplified model of the Fyn SH3 domain with a native-centric potential energy function. Analysis of the res...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC522025/ https://ncbi.nlm.nih.gov/pubmed/15469926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404436101 |
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