Perianal Crohn’s Disease is associated with distal colonic disease, stricturing disease behavior, IBD-associated serologies and genetic variation in the JAK-STAT pathway

BACKGROUND: Perianal Crohn’s Disease (pCD) is a particularly severe phenotype associated with poor quality of life with a reported prevalence of 12%–40%. Previous studies investigating the etiology of pCD have been limited in the numbers of subjects and the intensity of genotyping. The aim of this s...

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Publicado en:Inflamm Bowel Dis
Main Authors: Kaur, Manreet, Panikkath, Deepa, Yan, Xiaofei, Liu, Zhenqiu, Berel, Dror, Li, Dalin, Vasiliauskas, Eric A., Ippoliti, Andrew, Dubinsky, Marla, Shih, David Q., Melmed, Gil Y., Haritunians, Talin, Fleshner, Phillip, Targan, Stephan R., McGovern, Dermot P.B.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5220246/
https://ncbi.nlm.nih.gov/pubmed/26937622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000705
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