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Hedgehog inhibition enhances efficacy of radiation and cisplatin in orthotopic cervical cancer xenografts
BACKGROUND: The Hedgehog (Hh) pathway is upregulated in cervical cancer and associated with poor outcome. We explored the effects of Hh pathway inhibition in combination with RTCT in a patient derived orthotopic cervical cancer xenograft model (OCICx). METHODS: 5E1, a monoclonal antibody for SHH, or...
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| 出版年: | Br J Cancer |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5220149/ https://ncbi.nlm.nih.gov/pubmed/27875522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.383 |
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