Natural compounds targeting major cell signaling pathways: a novel paradigm for osteosarcoma therapy

Osteosarcoma is the most common primary bone cancer affecting children and adolescents worldwide. Despite an incidence of three cases per million annually, it accounts for an inordinate amount of morbidity and mortality. While the use of chemotherapy (cisplatin, doxorubicin, and methotrexate) in the...

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Udgivet i:J Hematol Oncol
Main Authors: Angulo, Pablo, Kaushik, Gaurav, Subramaniam, Dharmalingam, Dandawate, Prasad, Neville, Kathleen, Chastain, Katherine, Anant, Shrikant
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5219787/
https://ncbi.nlm.nih.gov/pubmed/28061797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-016-0373-z
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